R. Palinski

Inactivation of Highly Transmissible Livestock and Avian Viruses Including Influenza A and Newcastle Disease Virus for Molecular Diagnostics

This study shows that PrimeStore(R) molecular transport media inactivates viruses by >99.99% without affecting nucleic acid detection, enabling safer and more efficient diagnostic testing.

Beta human papillomavirus 8E6 promotes alternative end-joining

This study shows HPV8 E6 promotes alternative end-joining (Alt-EJ) by interacting with p300, leading to increased genomic instability and deletions with Alt-EJ signatures.

Beta HPV8 E6 Induces Micronuclei Formation and Promotes Chromothripsis

This paper shows HPV8 E6 induces genome instability through mitotic errors, leading to chromothripsis without UV exposure.

Beta human papillomavirus 8 E6 allows colocalization of non-homologous end joining and homologous recombination repair factors.

This study shows that beta HPV8 E6 causes abnormal DSB repair by allowing NHEJ and HR to occur at the same lesion, leading to increased genomic instability.

Into the deep (sequence) of the foot-and-mouth disease virus gene pool: bottlenecks and adaptation during infection in naïve and vaccinated cattle

This study analyzes FMDV quasispecies dynamics in vaccinated and non-vaccinated cattle, finding vaccination leads to early bottlenecks and reduced viral diversity, while non-vaccinated animals show more genetic diversity and adaptation.