Author

D. K. Rai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:chicken / avian· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. S. Anderson· 2 shared K. M. White· 2 shared R. D. Cardin· 2 shared A. Garcia-Sastre· 1 shared A. Gribenko· 1 shared B. Kreiswirth· 1 shared B. L. McGovern· 1 shared C. Stenfeldt· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMicrobiology

A. S. Anderson

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Author profile →

3 papers

Recent·Most cited

Nirmatrelvir, Molnupiravir, and Remdesivir maintain potent in vitro activity against the SARS-CoV-2 Omicron variant

R. Rosales, B. L. McGovern, M. L. Rodriquez, D. K. Rai, R. D. Cardin, A. S. Anderson, E. M. Sordillo, H. van Bakel, V. Simon, A. Garcia-Sastre, K. M. White

This study evaluates the antiviral activity of nirmatrelvir, molnupiravir, and remdesivir against the SARS-CoV-2 Omicron variant and confirms their potency.

bioRxiv · Jan 17, 2022 · PreprintMicrobiology

Nirmatrelvir, an orally active Mpro inhibitor, is a potent inhibitor of SARS-CoV-2 Variants of Concern

D. K. Rai, I. Yurgelonis, P. McMonagle, H. A. Rothan, L. Hao, A. Gribenko, E. Titova, B. Kreiswirth, K. M. White, Y. Zhu, A. S. Anderson, R. D. Cardin

This paper evaluates the antiviral activity of Nirmatrelvir against multiple SARS-CoV-2 variants using qRT-PCR in VeroE6 cells, showing potent inhibition across all tested variants.

bioRxiv · Jan 17, 2022Microbiology

The evolution of a super-swarm of foot-and-mouth disease virus in cattle

J. Arzt, I. Fish, S. J. Pauszek, S. L. Johnson, P. S. Chain, D. K. Rai, E. Rieder, T. L. Goldberg, L. L. Rodriguez, C. Stenfeldt

This study tracks FMDV evolution in cattle, finding that viral haplotypes shift early in infection but stabilize later, with mutations and minority haplotype emergence driving diversity.

bioRxiv · Jan 4, 2019Microbiology