TRIM14 is a key regulator of the type I interferon response during Mycobacterium tuberculosis infection
C. T. Hoffpauir, S. L. Bell, K. O. West, T. Jing, S. Torres-Odio, J. S. Cox, A. P. West, P. Li, K. L. Patrick, R. O. Watson
This study identifies TRIM14 as a negative regulator of the type I interferon response in macrophages during Mycobacterium tuberculosis infection, showing it enhances resolution of the response and limits bacterial replication.
The Journal of Immunology · Jul 1, 2020Peer-reviewedImmunology