Identification of NanoLuciferase Substrates Transported by Human ABCB1 and ABCG2 and their Zebrafish Homologs at the Blood-Brain Barrier
C. T. Inglut, J. A. Quinlan, R. W. Robey, J. R. Thomas, J. R. Walker, W. Zhou, H.-C. Huang, M. M. Gottesman
The paper identifies NanoLuciferase substrates transported by human and zebrafish ABC transporters at the BBB, aiding in the development of a transgenic zebrafish model to detect BBB disruptors.
bioRxiv · Oct 20, 2023 · PreprintPharmacology & Toxicology