Impaired islet function with normal exocrine enzyme secretion is consistent across the head, body, and tail pancreas regions in type 1 diabetes
D. Drotar, A. K. Mojica-Avila, D. T. Bloss, C. M. Cohrs, C. T. Manson, A. L. Posgai, M. D. Williams, M. A. Brusko, E. A. Phelps, C. H. Wasserfall, S. Speier, M. A. Atkinson
The paper examines islet and acinar cell secretion in different pancreatic regions across diabetes stages, finding reduced insulin secretion and beta-cell volume in T1D with normal enzyme secretion.
bioRxiv · Feb 8, 2024 · PreprintPathology