E. A. Phelps

Impaired islet function with normal exocrine enzyme secretion is consistent across the head, body, and tail pancreas regions in type 1 diabetes

The paper examines islet and acinar cell secretion in different pancreatic regions across diabetes stages, finding reduced insulin secretion and beta-cell volume in T1D with normal enzyme secretion.

Serum from pregnant donors induces human beta cell proliferation and insulin secretion

This study shows that serum from pregnant donors can stimulate human beta cell proliferation and insulin secretion, suggesting potential for beta cell expansion.

Immune engineered extracellular vesicles to modulate T cell activation in the context of type 1 diabetes

This study generates engineered extracellular vesicles to modulate T cell activation in type 1 diabetes by presenting HLA-A2 and costimulatory molecules, showing they can activate or suppress CD8+ T cells depending on PD-L1 presence.

Human threat learning is associated with gut microbiota composition

The paper investigates the relationship between gut microbiota composition and threat learning in humans, finding that threat learning varies with microbiome composition while safety learning does not.