Rapid development of an infant-derived HIV-1 broadly neutralizing antibody lineage
C. A. Simonich, L. Doepker, D. Ralph, J. A. Williams, A. Dhar, Z. Yaffe, L. Gentles, C. T. Small, B. Oliver, V. Vigdorovich, V. Mangala Prasad, R. Nduati, D. N. Sather, K. K. Lee, F. A. Matsen, J. Overbaugh
This study reconstructs the developmental lineage of an infant-derived HIV-1 broadly neutralizing antibody, showing a rapid evolution with fewer mutations compared to adult antibodies.
bioRxiv · Sep 13, 2018Immunology