Author

V. Mangala Prasad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Assay:cryo-EM· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Assay:proteomics· 2 Organism:virus· 2 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1

Frequent Co-Authors

K. K. Lee· 4 shared A. Dhar· 2 shared A. S. Dingens· 1 shared B. Oliver· 1 shared C. A. Simonich· 1 shared C. T. Small· 1 shared D. Arenz· 1 shared D. K. Ralph· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersBiophysics

K. K. Lee

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery

V. Mangala Prasad, J. S. Blijleven, J. M. Smit, K. K. Lee

This study visualizes the membrane fusion process of Chikungunya virus using cryo-electron tomography, revealing conformational changes and structural features of the fusion machinery.

bioRxiv · Mar 12, 2022 · PreprintBiophysics

Cryo-ET of HIV reveals Env positioning on Gag lattice and structural variation among Env trimers

V. Mangala Prasad, D. P. Leaman, K. N. Lovendahl, J. T. Croft, M. A. Benhaim, E. A. Hodge, M. B. Zwick, K. K. Lee

This study uses cryo-ET to analyze HIV-1 Env structure and positioning in mature and immature virions, revealing structural variation and insights into Env incorporation and antigen presentation.

bioRxiv · Aug 31, 2021Biophysics

Functional development of a V3-specific broadly neutralizing antibody isolated from a case of HIV superinfection

M. M. Shipley, V. Mangala Prasad, L. E. Doepker, A. S. Dingens, D. K. Ralph, E. Harkins, A. Dhar, D. Arenz, V. Chohan, H. Weight, K. Mandaliya, J. D. Bloom, F. Matsen, K. K. Lee, J. M. Overbaugh

This study characterizes the development of a V3-specific broadly neutralizing antibody from an HIV superinfection case, revealing unique epitope recognition and escape mechanisms.

bioRxiv · Mar 15, 2021Microbiology

Rapid development of an infant-derived HIV-1 broadly neutralizing antibody lineage

C. A. Simonich, L. Doepker, D. Ralph, J. A. Williams, A. Dhar, Z. Yaffe, L. Gentles, C. T. Small, B. Oliver, V. Vigdorovich, V. Mangala Prasad, R. Nduati, D. N. Sather, K. K. Lee, F. A. Matsen, J. Overbaugh

This study reconstructs the developmental lineage of an infant-derived HIV-1 broadly neutralizing antibody, showing a rapid evolution with fewer mutations compared to adult antibodies.

bioRxiv · Sep 13, 2018Immunology