Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy
Y. Zhang, Z. R. Gregorich, Y. Wang, C. U. Braz, J. Zhang, Y. Liu, P. Liu, N. Aori, T. A. Hacker, H. Granzier, W. Guo
This study identifies disruption of the nuclear localization signal in RBM20 as a causative mechanism in dilated cardiomyopathy through impaired nucleocytoplasmic transport.
bioRxiv · Dec 8, 2022Cell Biology