Author

Z. R. Gregorich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

W. Guo· 2 shared C. U. Braz· 1 shared D. S. Roberts· 1 shared D. Wang· 1 shared E. A. Chapman· 1 shared E. J. Larson· 1 shared G. M. Diffee· 1 shared H. Granzier· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

W. Guo

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Author profile →

2 papers

Recent·Most cited

High Sensitivity Top-down Proteomics Captures Single Muscle Cell Heterogeneity in Large Proteoforms

J. A. Melby, K. A. Brown, Z. R. Gregorich, D. S. Roberts, E. A. Chapman, L. E. Ehlers, Z. Gao, E. J. Larson, Y. Jin, J. Lopez, J. Hartung, Y. Zhu, D. Wang, W. Guo, G. M. Diffee, Y. Ge

This study develops a sensitive top-down proteomics method to analyze large proteoforms in single muscle cells, revealing heterogeneity and linking it to muscle fiber types.

bioRxiv · Dec 29, 2022 · PreprintBiochemistry

Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy

Y. Zhang, Z. R. Gregorich, Y. Wang, C. U. Braz, J. Zhang, Y. Liu, P. Liu, N. Aori, T. A. Hacker, H. Granzier, W. Guo

This study identifies disruption of the nuclear localization signal in RBM20 as a causative mechanism in dilated cardiomyopathy through impaired nucleocytoplasmic transport.

bioRxiv · Dec 8, 2022Cell Biology