Intravenous Immunization with Triple Auxotrophs of Mycobacterium tuberculosis: A novel vaccine strategy against tuberculosis
C. Vilcheze, S. Rajagopalan, W. R. Jacobs
This paper investigates a novel tuberculosis vaccine strategy using a triple auxotrophic Mtb strain, showing intravenous immunization provides superior protection compared to subcutaneous BCG in mice.
bioRxiv · May 15, 2024 · PreprintMicrobiology