Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis
V. Panic, S. Pearson, J. Banks, T. S. Tippetts, S. Lee, J. Simcox, G. Geoghegan, C. Bensard, T. van Ry, W. L. Holland, S. Summers, J. Cox, G. Ducker, J. Rutter, C. Villanueva
This study shows that mitochondrial pyruvate carrier is essential for optimal brown fat thermogenesis, as its deletion impairs cold adaptation and alters metabolic pathways.
bioRxiv · Oct 29, 2019Biochemistry