Author

T. Van Ry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

J. A. Maschek· 2 shared J. Cox· 2 shared J. E. Cox· 2 shared J. Rutter· 2 shared A. A. Cluntun· 1 shared A. Chawla· 1 shared B. Rajwa· 1 shared B. Wang· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPhysiology

J. A. Maschek

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Author profile →

4 papers

Recent·Most cited

Trade-Offs Between Hepatic Host Defense and Metabolic Programs Underlie Sex-Biased Diseases

J. Nikkanen, Y. A. Leong, W. C. Krause, D. Dermadi, J. A. Maschek, T. Van Ry, J. Cox, E. Weiss, O. Gokcumen, A. Chawla, H. Ingraham

This study identifies a sex-dependent trade-off between hepatic host defense and metabolic programs in mice, showing that BCL6 protects males from infection but increases metabolic disease risk under dietary excess.

bioRxiv · Jan 7, 2022Physiology

Network-aware reaction pattern recognition reveals regulatory signatures of mitochondrial dysfunction

J. A. Berg, Y. Zhou, Y. Ouyang, T. C. Waller, A. A. Cluntun, M. E. Conway, S. M. Nowinski, T. Van Ry, I. George, J. E. Cox, B. Wang, J. Rutter

The paper introduces Metaboverse, a tool for network-aware reaction pattern recognition in metabolic data, identifying regulatory signatures of mitochondrial dysfunction in lung adenocarcinoma and respiratory deficiency models.

bioRxiv · Jun 25, 2020 · PreprintBiochemistry

Schistosoma mansoni infection reprograms the metabolic potential of the myeloid lineage in a mouse model of metabolic syndrome

D. Cortes-Selva, L. Gibbs, J. A. Maschek, T. Van Ry, B. Rajwa, J. E. Cox, E. Amiel, K. C. Fairfax

This study shows that Schistosoma mansoni infection reprograms myeloid cell metabolism in male mice, with sex-dependent effects on cholesterol and glucose metabolism.

bioRxiv · Apr 20, 2020 · PreprintImmunology

Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis

V. Panic, S. Pearson, J. Banks, T. S. Tippetts, S. Lee, J. Simcox, G. Geoghegan, C. Bensard, T. van Ry, W. L. Holland, S. Summers, J. Cox, G. Ducker, J. Rutter, C. Villanueva

This study shows that mitochondrial pyruvate carrier is essential for optimal brown fat thermogenesis, as its deletion impairs cold adaptation and alters metabolic pathways.

bioRxiv · Oct 29, 2019Biochemistry