O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control
D. M. F. van Aalten, C. W. Mitchell, H. Yuan, F. Authier, M. Sonderstrup-Jensen, A. T. Ferenbach, A. M. d'Alessio
The paper identifies O-GlcNAcylation of DDX3X as a regulator of the G1/S-phase transition and shows its role in cell cycle control and neurogenesis in OGT-CDG.
bioRxiv · Feb 28, 2024Cell Biology