Author

A. T. Ferenbach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. M. F. van Aalten· 3 shared C. W. Mitchell· 2 shared A. Gorelik· 1 shared A. M. d'Alessio· 1 shared C. Scavenius· 1 shared D. A. Robinson· 1 shared D. Boldovjakova· 1 shared D. E. A. Lockhart· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCell Biology

D. M. F. van Aalten

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control

D. M. F. van Aalten, C. W. Mitchell, H. Yuan, F. Authier, M. Sonderstrup-Jensen, A. T. Ferenbach, A. M. d'Alessio

The paper identifies O-GlcNAcylation of DDX3X as a regulator of the G1/S-phase transition and shows its role in cell cycle control and neurogenesis in OGT-CDG.

bioRxiv · Feb 28, 2024Cell Biology

Exploiting O-GlcNAc Transferase promiscuity to dissect site-specific O-GlcNAcylation

C. W. Mitchell, S. G. Bartual, A. T. Ferenbach, C. Scavenius, D. M. F. van Aalten

This study develops a method to produce site-specific, homogeneous mono-glycosylated proteins for studying O-GlcNAcylation using OGT's tolerance for cysteine and co-expressed OGA.

bioRxiv · Jul 31, 2023Biochemistry

CRISPR-Cas9-mediated depletion of O-GlcNAc hydrolase and transferase for functional dissection of O-GlcNAcylation in human cells

A. Gorelik, A. T. Ferenbach

This study uses CRISPR-Cas9 to deplete OGT and OGA in human cells, revealing compensatory changes in enzyme expression and O-GlcNAcylation levels.

bioRxiv · Aug 19, 2020 · PreprintBiochemistry

Targeting a critical step in fungal hexosamine biosynthesis

D. E. A. Lockhart, M. Stanley, O. G. Raimi, D. A. Robinson, D. Boldovjakova, D. R. Squair, A. T. Ferenbach, W. Fang, D. M. F. van Aalten

This study identifies Gna1 as an antifungal target in Aspergillus fumigatus by showing its essential role in cell wall synthesis and demonstrating a chemical inhibitor.

bioRxiv · Jan 7, 2020Microbiology