Author

C.-C. D. Cho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

K. S. Yang· 2 shared S. Xu· 2 shared W. R. Liu· 2 shared Y. Qiao· 2 shared E. C. Vatansever· 1 shared G. Yu· 1 shared H. Ji· 1 shared N. Shaabani· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

K. S. Yang

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2 papers

Recent·Most cited

Cellular Activities of SARS-CoV-2 Main Protease Inhibitors Reveal Their Unique Characteristics

W. Cao, C.-C. D. Cho, Z. Z. Geng, X. R. Ma, R. Allen, N. Shaabani, E. C. Vatansever, Y. R. Alugubelli, Y. Ma, W. H. Ellenburg, K. S. Yang, Y. Qiao, H. Ji, S. Xu, W. R. Liu

This paper evaluates the cellular potency of SARS-CoV-2 MPro inhibitors using a fluorescent flow cytometry assay, revealing that most inhibitors have weak cellular activity despite strong antiviral effects.

bioRxiv · Jun 8, 2021 · PreprintBiochemistry

Drug Repurposing for the SARS-CoV-2 Papain-Like Protease

C.-C. D. Cho, S. G. Li, K. S. Yang, T. J. Lalonde, G. Yu, Y. Qiao, S. Xu, W. R. Liu

This study screens inhibitors against SARS-CoV-2 PLpro, identifying several potent compounds with IC50 values below 60 μM, including SJB2-043 with an IC50 of 0.56 μM.

bioRxiv · Jun 4, 2021Biochemistry