Author

T. J. Lalonde

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

S. Xu· 2 shared W. R. Liu· 2 shared C. M. Roundy· 1 shared C.-C. D. Cho· 1 shared G. L. Hamer· 1 shared G. Yu· 1 shared J. M. Tharp· 1 shared J. T. Hampton· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

S. Xu

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2 papers

Recent·Most cited

A Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2

J. T. Hampton, T. J. Lalonde, J. M. Tharp, Y. R. Alugubelli, C. M. Roundy, G. L. Hamer, S. Xu, W. R. Liu, Y. Kurra

This study constructs and validates a phage-displayed macrocyclic peptide library using regioselective chemical reactions and identifies a potent SARS-CoV-2 neutralizing peptide through epitope-directed selection.

bioRxiv · Jul 6, 2022Biochemistry

Drug Repurposing for the SARS-CoV-2 Papain-Like Protease

C.-C. D. Cho, S. G. Li, K. S. Yang, T. J. Lalonde, G. Yu, Y. Qiao, S. Xu, W. R. Liu

This study screens inhibitors against SARS-CoV-2 PLpro, identifying several potent compounds with IC50 values below 60 μM, including SJB2-043 with an IC50 of 0.56 μM.

bioRxiv · Jun 4, 2021Biochemistry