Author

C.-L. Lin

Primary ORCID profile (0009-0004-3948-2307 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

C.-L. LiniD1 paper · Broad Institute

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scATAC-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Atrazhev· 1 shared C.-M. Wang· 1 shared E. A. Volker· 1 shared E. J. Carpenter· 1 shared E. S. Hayhoe· 1 shared J. Ruan· 1 shared K. Mitsuya· 1 shared M. Kusi· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Atrazhev

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2 papers

Recent·Most cited

Chemoenzymatic Synthesis of Genetically-Encoded Multivalent Liquid N-glycan Arrays

C.-L. Lin, M. Sojitra, E. J. Carpenter, E. S. Hayhoe, S. Sarkar, E. A. Volker, A. Atrazhev, T. L. Lowary, M. S. Macauley, R. Derda

This paper develops a method to synthesize genetically-encoded multivalent liquid N-glycan arrays and evaluates their interaction with glycan-binding proteins in vitro and in vivo.

bioRxiv · Aug 5, 2022Biochemistry

Single-cell chromatin profiling reveals demethylation-dependent metabolic vulnerabilities of breast cancer epigenome

M. Kusi, M. Zand, C.-L. Lin, C.-M. Wang, N. D. Lucio, N. B. Kirma, J. Ruan, T. H.- M. Huang, K. Mitsuya

This study uses scATAC-seq to show 2HG enantiomers disrupt DNA and histone demethylation, leading to epigenetic changes in breast cancer cells.

Cell Reports · Jan 1, 2022Peer-reviewedCancer Biology