Author

T. L. Lowary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

M. S. Macauley· 3 shared S. Sarkar· 3 shared E. J. Carpenter· 2 shared M. Sojitra· 2 shared R. B. Zheng· 2 shared R. Derda· 2 shared A. Atrazhev· 1 shared A. Khalil· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBiochemistry

M. S. Macauley

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Author profile →

5 papers

Recent·Most cited

Autoaggregation in Streptococcus intermedius is driven by the Pel polysaccharide

D. Raju, S. A. Turner, K. Castro, G. B. Whitfield, D. LaMarche, S. Mahajan, R. Pfoh, F. Le Mauff, M. Joe, S. Sarkar, T. L. Lowary, D. C. Sheppard, D. J. Wozniak, M. G. Surette, P. L. Howell

This study identifies the Pel polysaccharide as a driver of autoaggregation in S. intermedius, linking it to biofilm formation and increased pathogenicity.

mBio · Aug 13, 2025Peer-reviewedMicrobiology

Chemoenzymatic Synthesis of Genetically-Encoded Multivalent Liquid N-glycan Arrays

C.-L. Lin, M. Sojitra, E. J. Carpenter, E. S. Hayhoe, S. Sarkar, E. A. Volker, A. Atrazhev, T. L. Lowary, M. S. Macauley, R. Derda

This paper develops a method to synthesize genetically-encoded multivalent liquid N-glycan arrays and evaluates their interaction with glycan-binding proteins in vitro and in vivo.

bioRxiv · Aug 5, 2022Biochemistry

Sialic acid-Dependent Binding and Viral Entry of SARS-CoV-2

L. Nguyen, K. A. McCord, D. T. Bui, K. A. Bouwman, E. N. Kitova, D. Kumawat, G. C. Daskan, I. Tomris, L. Han, P. Chopra, T.-J. Yang, S. D. Williows, T. L. Lowary, L. J. West, S.-T. D. Hsu, , J. S. Klassen

This study shows SARS-CoV-2 RBD binds sialylated glycans, particularly gangliosides, and that reducing cell surface sialic acid decreases viral entry.

bioRxiv · Mar 8, 2021Biochemistry

Genetically Encoded, Multivalent Liquid Glycan Array (LiGA)

M. Sojitra, S. Sarkar, J. Maghera, E. Rodrigues, E. J. Carpenter, S. Seth, D. F. Vinals, N. J. Bennett, R. Reddy, A. Khalil, X. Xue, M. Bell, R. B. Zheng, P. Zhang, C. Nycholat, , R. Derda

The paper introduces LiGA, a platform for analyzing glycan-lectin interactions using DNA barcoded phage displaying glycans, enabling in vitro and in vivo binding studies.

bioRxiv · Mar 24, 2020Biochemistry

Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria

Y. Z. Tan, L. Zhang, J. Rodrigues, R. B. Zheng, S. I. Giacometti, A. L. Rosario, B. Kloss, V. P. Dandey, H. Wei, R. Brunton, A. M. Raczkowski, D. Athayde, M. J. Catalao, M. Pimentel, O. B. Clarke, , F. Mancia

The paper presents the cryo-EM structure of AftD from M. abscessus and shows its interaction with ACP, revealing potential regulatory mechanisms.

bioRxiv · Dec 22, 2019Biochemistry