Intraplacental injection of human iPSC-derived PDX1+ pancreatic progenitors prolongs Pdx1-deficient mice survival
A. Wakimoto, Z. J. Shahri, H. Jeon, T. Hayashi, C.-W. Liao, N. Gogoleva, F. P. Suchy, A. Noda, Y. An, H. Nakauchi, Y. Hayashi, M. Hamada, S. Takahashi
This study transplants human iPSC-derived pancreatic progenitors into Pdx1-deficient mice, extending their lifespan and demonstrating functional engraftment of human pancreatic cells.
bioRxiv · May 9, 2024 · PreprintCell Biology