Author

C.-Y. Chung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

B. Bilanges· 1 shared C. O'Connor· 1 shared C. Tsui· 1 shared D. Wang· 1 shared E. Topley· 1 shared G. E. Valdebenito· 1 shared G. Erikson· 1 shared G. Szabadkai· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

B. Bilanges

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Author profile →

2 papers

Recent·Most cited

Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243A>G mtDNA mutation

C.-Y. Chung, K. Singh, V. N. Kotiadis, G. E. Valdebenito, J. H. Ahn, E. Topley, J. Tan, W. D. Andrews, B. Bilanges, R. D. S. Pitceathly, G. Szabadkai, M. Yuneva, M. R. Duchen

The paper shows that the m.3243A>G mtDNA mutation activates the PI3K-Akt-mTORC1 pathway, which can be inhibited to reduce mutant mtDNA load and improve cellular function.

bioRxiv · Jun 18, 2020 · PreprintCell Biology

Tuft cells restrain pancreatic tumorigenesis through paracrine eicosanoid signaling

K. E. DelGiorno, C.-Y. Chung, H. C. Maurer, S. Weiser Novak, R. R. Giraddi, D. Wang, R. F. Naeem, L. Fang, L. R. Andrade, N. K. Lytle, W. H. Ali, C. Tsui, V. B. Gubbala, M. Ridinger-Saison, M. Ohmoto, , G. Wahl

This study shows that tuft cells suppress pancreatic tumorigenesis by producing anti-inflammatory prostaglandin D2, which inhibits stromal activation, and identifies their protective role in early disease progression.

bioRxiv · Dec 19, 2019 · PreprintCancer Biology