Author

L. R. Andrade

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Organism:C. elegans· 1

Frequent Co-Authors

U. Manor· 5 shared H. C. Maurer· 2 shared K. E. DelGiorno· 2 shared K. P. Olive· 2 shared S. Weiser Novak· 2 shared A. Iuga· 1 shared A. Ma· 1 shared A. R. Decker· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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5 shared papersCell Biology

U. Manor

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Author profile →

6 papers

Recent·Most cited

Immunohistochemical and ultrastructural characterization of the inner ear epithelial cells of splitnose rockfish (Sebastes diploproa)

G. T. Kwan, K. J. Prime, L. R. Andrade, M. Tresguerres

This study characterizes the inner ear epithelial cell types and protein expression in splitnose rockfish to understand otolith biomineralization and its sensitivity to environmental factors.

bioRxiv · Sep 22, 2023Physiology

Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling

T. Chaiamarit, A. Verhelle, R. Chassefeyre, N. Shukla, S. Weiser Novak, L. R. Andrade, U. Manor, S. E. Encalada

This study identifies mutant PrP endoggresomes as hubs causing cytoskeletal and transport deficits in axons, leading to organelle retention and mitochondrial dysfunction in prionopathies.

bioRxiv · Mar 19, 2023 · PreprintCell Biology

A nesprin-4/kinesin-1 cargo model for nuclear positioning in cochlear outer hair cells

S. Taiber, O. Gozlan, R. Cohen, L. R. Andrade, E. F. Gregory, D. A. Starr, Y. Moran, R. Hipp, M. W. Kelley, U. Manor, D. Sprinzak, K. B. Avraham

This study identifies a conserved 4-amino-acid motif in nesprin-4 that mediates its interaction with kinesin-1, essential for nuclear positioning in outer hair cells and hearing.

bioRxiv · Oct 10, 2021Cell Biology

Tuft cells restrain pancreatic tumorigenesis through paracrine eicosanoid signaling

K. E. DelGiorno, C.-Y. Chung, H. C. Maurer, S. Weiser Novak, R. R. Giraddi, D. Wang, R. F. Naeem, L. Fang, L. R. Andrade, N. K. Lytle, W. H. Ali, C. Tsui, V. B. Gubbala, M. Ridinger-Saison, M. Ohmoto, , G. Wahl

This study shows that tuft cells suppress pancreatic tumorigenesis by producing anti-inflammatory prostaglandin D2, which inhibits stromal activation, and identifies their protective role in early disease progression.

bioRxiv · Dec 19, 2019 · PreprintCancer Biology

Induction of pancreatic tumor-selective ferroptosis through modulation of cystine import

M. A. Badgley, D. Kremer, H. C. Maurer, K. E. DelGiorno, H.-J. Lee, V. Purohit, I. Sagalovskiy, A. Ma, J. Kapillian, C. E. M. Firl, A. R. Decker, S. A. Sastra, C. F. Palermo, L. R. Andrade, P. Sajjakulnukit, , K. P. Olive

The paper shows that targeting cystine import induces ferroptosis in pancreatic tumors, leading to tumor regression and improved survival in a mouse model.

bioRxiv · Nov 1, 2019 · PreprintCancer Biology

Actin chromobody imaging reveals sub-organellar actin dynamics

C. R. Schiavon, T. Zhang, B. Zhao, L. R. Andrade, M. Wu, T.-C. Sung, Y. Dayn, J. W. Feng, O. A. Quintero, R. Grosse, U. Manor

The paper develops a method to image sub-organellar actin dynamics using fluorescent actin nanobodies and finds ER-associated actin drives organelle fission.

bioRxiv · Jun 25, 2019Cell Biology