Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset
Arian Mansur, Remi Joseph, Euri S Kim, Pierre M. Jean Beltran, Namrata D. Udeshi, Cadence Pearce, Hanjie Jiang, Reina Iwase, Miroslav P. Milev, Hashem A Almousa, Elyshia L. McNamara, Jeffrey J. Widrick, Claudio F. Pérez, Gianina Ravenscroft, Michael G. Sacher, , Vandana Gupta
This study identifies KLHL40 as a negative regulator of ER-Golgi trafficking through ubiquitylation, revealing its role in skeletal muscle development and disease.
eLife · Jan 1, 2022Peer-reviewedGenetics