Pierre M. Jean Beltran

The paper uses single-nucleus multi-omics to study skeletal muscle changes in HFpEF patients and shows some molecular changes are reversible with lifestyle interventions.

The paper maps the Drosophila secretome to identify tissue-specific origins and inter-organ trafficking of 535 blood plasma proteins.

The paper identifies tissue-specific transcriptional regulatory programs in rats undergoing endurance exercise training by integrating chromatin accessibility, DNA methylation, and gene expression data.

CoSpred is a machine learning workflow that predicts complete tandem mass spectra from peptide sequences, improving spectral library matching by including non-backbone ions.

This study examines how endurance exercise training affects rat subcutaneous white adipose tissue, revealing sex-specific molecular responses and differences in adiposity and metabolism.

This study maps multi-omic mitochondrial changes across 19 tissues in rats after endurance exercise training, identifying tissue-specific adaptations and disease-related hubs.

This study profiles multi-omic changes in multiple tissues of rats during endurance exercise training, identifying molecular adaptations and sex-specific responses across time.

This study identifies KLHL40 as a negative regulator of ER-Golgi trafficking through ubiquitylation, revealing its role in skeletal muscle development and disease.