ACE2 utilization of HKU25 clade MERS-related coronaviruses with broad geographic distribution
Chen Liu, Young‐Jun Park, Chengbao Ma, Cameron Stuart, Risako Gen, Yucheng Sun, Xiao Yi Yang, M C Lin, Qing Xiong, Jun-Yu Si, Peng Liu, David Veesler, Huan Yan
The paper shows that HKU25 clade MERS-related coronaviruses use ACE2 as a receptor, challenging prior beliefs that DPP4 was their main receptor.
bioRxiv · Feb 19, 2025 · PreprintMicrobiology