Author

Chengbao Ma

Wuhan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Organism:mouse· 1 Organism:multiple species· 1

Frequent Co-Authors

Chen LiuiD· 3 shared Huan YaniD· 3 shared David VeesleriD· 2 shared Peng LiuiD· 2 shared Qing XiongiD· 2 shared Risako GeniD· 2 shared Young‐Jun ParkiD· 2 shared Yucheng SuniD· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Chen LiuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Convergent utilization of APN receptor by hedgehog merbecoviruses

Peng Liu, Qianhui Zhu, Jingyi Liu, Zhixing Ma, Yuanling Yu, Chen Liu, Chengbao Ma, Junyu Si, Xiao Ping Yang, Meiling Huang, Yehui Sun, Yu Xiao, Yucheng Sun, Tianci Liu, Lingling Yu, , Huan Yan

The paper identifies hedgehog APN as a receptor for EriCoVs and shows convergent evolution in its utilization among merbecoviruses.

bioRxiv · Sep 16, 2025 · PreprintMolecular Biology

ACE2 utilization of HKU25 clade MERS-related coronaviruses with broad geographic distribution

Chen Liu, Young‐Jun Park, Chengbao Ma, Cameron Stuart, Risako Gen, Yucheng Sun, Xiao Yi Yang, M C Lin, Qing Xiong, Jun-Yu Si, Peng Liu, David Veesler, Huan Yan

The paper shows that HKU25 clade MERS-related coronaviruses use ACE2 as a receptor, challenging prior beliefs that DPP4 was their main receptor.

bioRxiv · Feb 19, 2025 · PreprintMicrobiology

Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses

Young‐Jun Park, Chen Liu, Jimin Lee, Jack T Brown, Chengbao Ma, Peng Liu, Risako Gen, Qing Xiong, Samantha K. Zepeda, Cameron Stewart, Amin Addetia, Caroline J. Craig, M. Alejandra Tortorici, Abeer N. Alshukairi, Tyler N. Starr, , David Veesler

HKU5 merbecoviruses use bat Pipistrellus abramus ACE2 and several artiodactyl ACE2s through a cryo-EM-defined binding mode distinct from other ACE2-using coronaviruses, showing independent evolution of ACE2 usage.

Cell · Feb 7, 2025Peer-reviewedBiochemistry✦ In-depth digest