Identification of Novel Modulators of the ALT Pathway Through a Native FISH-Based Optical Screen
Benura Azeroglu, Simran Khurana, Shih-Chun Wang, Gianna M. Tricola, Shalu Sharma, Camille Jubelin, Ylenia Cortolezzis, Gianluca Pegoraro, Kyle M. Miller, Travis H. Stracker, Eros Lazzerini Denchi
This study identifies novel genes that modulate the ALT pathway using a high-throughput imaging screen, revealing both promoting and inhibiting factors and demonstrating pharmacological modulation potential.
Cell Reports · Dec 26, 2024Peer-reviewedMolecular Biology