Author

Shih-Chun Wang

The University of Texas at Austin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

Kyle M. MilleriD· 2 shared Baylee A. SmithiD· 1 shared Benura AzerogluiD· 1 shared Camille Jubelin· 1 shared Chan Hyun NaiD· 1 shared Daein Kim· 1 shared Darpan MedhiiD· 1 shared Doohyung Lee· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Kyle M. MillerORCID

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Author profile →

3 papers

Recent·Most cited

Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks

Samantha B. Regan, Darpan Medhi, Yuanlin Xu, Travis White, Yi-Zhen Jiang, Jung Eun Kim, Shih-Chun Wang, Qichen Deng, Jia Su, Dulguun Baasan, Jon P. Connelly, Ti‐Cheng Chang, Shondra M. Pruett‐Miller, Maria Jasin

This study investigates LOH caused by CRISPR-Cas9 DSBs, showing large-scale loss and mechanisms, and highlights risks when combined with end joining inhibition.

Molecular Cell · Nov 1, 2025Peer-reviewedMolecular Biology

Identification of Novel Modulators of the ALT Pathway Through a Native FISH-Based Optical Screen

Benura Azeroglu, Simran Khurana, Shih-Chun Wang, Gianna M. Tricola, Shalu Sharma, Camille Jubelin, Ylenia Cortolezzis, Gianluca Pegoraro, Kyle M. Miller, Travis H. Stracker, Eros Lazzerini Denchi

This study identifies novel genes that modulate the ALT pathway using a high-throughput imaging screen, revealing both promoting and inhibiting factors and demonstrating pharmacological modulation potential.

Cell Reports · Dec 26, 2024Peer-reviewedMolecular Biology

TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling

Daein Kim, Ragini Bhargava, Shih-Chun Wang, Wei-Che Tseng, Doohyung Lee, Riya Patel, Sungtaek Oh, Ray W. Bowman, Baylee A. Smith, Min Kyu Kim, Chan Hyun Na, Roderick J. O’Sullivan, Kyle M. Miller

This study identifies TRIM24's role in ALT telomere maintenance through chromatin signaling, showing it promotes telomere DNA synthesis via SUMO-dependent mechanisms.

Molecular Cell · Jan 1, 2024Peer-reviewedCell Biology