Author

Carole Manneville

Novartis (Switzerland)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Gilles SansigiD· 2 shared Zacharias ThieliD· 2 shared Alexandra Hinniger· 1 shared Alexandra Lavoisier· 1 shared Alexandra ProbstiD· 1 shared Alexandro LandshammeriD· 1 shared Beat NyfeleriD· 1 shared Benedikt GoretzkiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Gilles SansigORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 19, 2026

GPNMB enables lysosomal adaptation required for myelin clearance and nerve regeneration after peripheral nerve injury

Najwa Ouali Alami, Moh Panesar, Michael Obrecht…·Michael Bidinosti

This study identifies GPNMB as a critical regulator of lysosomal function in macrophages, essential for myelin clearance and nerve regeneration after peripheral nerve injury.

DOI 10.64898/2026.10.12.758439

mouseexperimental assay

𝕏 PostBluesky

Synthetic BiologyNature CommunicationsPeer-reviewedDec 3, 2025

Development of a p62 biodegrader for autophagy targeted degradation

Zacharias Thiel, David Marcellin, Carole Manneville…·Beat Nyfeler

The paper develops a p62-based biodegrader that selectively degrades mitochondria via autophagy but not cytosolic proteins due to its effect on p62 self-oligomerization.

9 citationstop 3%

experimental assaydrug response / drug discovery

𝕏 PostBluesky