Author

Beat Nyfeler

Novartis (Switzerland)ORCID 0000-0003-0624-9571Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexandra Hinniger· 1 shared Alexandra Lavoisier· 1 shared Alexandra ProbstiD· 1 shared Alexandro LandshammeriD· 1 shared Benedikt GoretzkiiD· 1 shared Carole Manneville· 1 shared Catrin Swantje MülleriD· 1 shared Celine Be· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Alexandra Hinniger

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1 paper

Recent·Most cited

Synthetic BiologyNature CommunicationsPeer-reviewedDec 3, 2025

Development of a p62 biodegrader for autophagy targeted degradation

Zacharias Thiel, David Marcellin, Carole Manneville…·Beat Nyfeler

The paper develops a p62-based biodegrader that selectively degrades mitochondria via autophagy but not cytosolic proteins due to its effect on p62 self-oligomerization.

9 citationstop 3%

experimental assaydrug response / drug discovery

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