Chemical History Shapes the Antigenic Identity of MHC-I Epitopes
Sarah E. Newkirk, Joey J. Kelly, Karl L. Ocius, Carson Starnes, Sameek Singh, Tian Zhang, Marcos M. Pires
The paper shows that chemical modifications of MHC-I epitopes affect T cell recognition, demonstrating that antigenic identity depends on both sequence and chemical history.
bioRxiv · Nov 6, 2025 · PreprintImmunology