Author
University of Virginia
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Sarah E. Newkirk, Joey J. Kelly, Nita Hourn…·Marcos M. Pires
This paper evaluates peptidomimetic modifications of MHC-I epitopes to improve antigen design, finding position-dependent tolerance and non-additive effects on immunogenicity and pharmacokinetics.
Sarah E. Newkirk, Joey J. Kelly, Karl L. Ocius…·Marcos M. Pires
The paper shows that chemical modifications of MHC-I epitopes affect T cell recognition, demonstrating that antigenic identity depends on both sequence and chemical history.
Sarah E. Newkirk, Joey J. Kelly, Mahendra D. Chordia…·Marcos M. Pires
The paper identifies Hsp90 inhibitors as MHC-I inducers and develops novel compounds using click chemistry to enhance T cell activation and reduce toxicity.