Author

Catherine Ross

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:CRISPR screen· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Amy H.Y. TongiD· 3 shared Brenda AndrewsiD· 3 shared Chad L. MyersiD· 3 shared Charles M. BooneiD· 3 shared Jason MoffatiD· 3 shared Katherine ChaniD· 3 shared Keith A. LawsoniD· 3 shared Kevin R. BrowniD· 3 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Amy H.Y. TongORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Systemic neoantigen-specific T cells reveal central determinants of PD-(L)1 blockade efficacy

Célia Ramade, Noémie Thébault, Clara‐Maria Scarlata, Daniel Oreper, Françoise Lauzéral-Vizcaïno, Suchit Jhunjhunwala, Bastien Cabarrou, Milena Hornburg, Caroline Fournier, Anna Salvioni, Marie Michelas, Victor Sarradin, Giulia Costanza Leonardi, Virginie Féliu, Myriam Maixent, , Maha Ayyoub

The paper identifies coordinated neoantigen-specific CD8 T cell responses as key predictors of PD-(L)1 therapy efficacy in non-small cell lung cancer patients.

bioRxiv · Mar 12, 2026 · PreprintCancer Biology

Quantitative analysis of genetic interactions in human cells from genome-wide CRISPR-Cas9 screens

Maximilian Billmann, Michael Costanzo, Mahfuzur Rahman, Katherine Chan, Amy H.Y. Tong, Henry N. Ward, Arshia Zernab Hassan, Xiang Zhang, Kevin R. Brown, Thomas Rohde, Angela Helen Shaw, Catherine Ross, Jolanda S. van Leeuwen, Michael Aregger, Keith A. Lawson, , Chad L. Myers

The paper develops a method to quantify genetic interactions from CRISPR-Cas9 screens and identifies systematic variations in screen data.

bioRxiv · Jun 30, 2025 · PreprintBioinformatics

A global genetic interaction map of a human cell reveals conserved principles of genetic networks

Maximilian Billmann, Michael Costanzo, Xiang Zhang, Arshia Zernab Hassan, Mahfuzur Rahman, Kevin R. Brown, Katherine Chan, Amy H.Y. Tong, Carles Pons, Henry N. Ward, Catherine Ross, Jolanda S. van Leeuwen, Michael Aregger, Keith A. Lawson, Barbara Mair, , Charles M. Boone

The paper constructs a genome-scale genetic interaction network from 4 million double mutants in HAP1 cells, revealing conserved genetic network principles across species and uncovering novel gene functions and cancer dependencies.

bioRxiv · Jun 30, 2025 · PreprintSystems Biology

Systematic mapping of genetic interactions for de novo fatty acid synthesis

Michael Aregger, Keith A. Lawson, Maximilian Billmann, Michael Costanzo, Amy H.Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Ušaj, Lucy Nedyalkova, Olga S. Sizova, Andrea Habsid, Judy Pawling, Zhen‐Yuan Lin, , Jason Moffat

This study maps genetic interactions in FASN-deficient cells to identify genes involved in lipid uptake and metabolic adaptation.

Nature Metabolism · Jun 1, 2020Peer-reviewedSystems Biology