The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip
Sarah Watkins, Karen M. Ho, Christian Testa, Louise Falk, Patrice Soule, Linda V. Nguyen, Sophie FitzGibbon, Catherine Slack, Jarvis T. Chen, George Davey Smith, Immaculata De Vivo, Andrew J. Simpkin, Kate M. Tilling, Pamela D. Waterman, Nancy Krieger, , Caroline Laura Relton
This study evaluates the reliability of DNA methylation measurements using the Illumina Infinium MethylationEPIC BeadChip at low DNA input levels, finding that 40ng DNA can be used with quality checks.
Epigenetics · Oct 14, 2022Peer-reviewedBioinformatics