Author

Louise Falk

University of Bristol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

George Davey SmithiD· 3 shared Claes OhlssoniD· 2 shared Eleftheria ZegginiiD· 2 shared George V. DedoussisiD· 2 shared Ingrid GergeiiD· 2 shared Jie ZhengiD· 2 shared Jonathan H. TobiasiD· 2 shared Kaare Morten GautvikiD· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

George Davey SmithORCID

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Author profile →

3 papers

Recent·Most cited

Lowering of circulating sclerostin may increase risk of atherosclerosis and its risk factors: evidence from a genome-wide association meta-analysis followed by Mendelian randomization

Jie Zheng, Eleanor Wheeler, Maik Pietzner, Till F. M. Andlauer, Michelle S. Yau, April E. Hartley, Ben Michael Brumpton, Humaira Rasheed, John P. Kemp, Monika Frysz, Jamie W. Robinson, Sjur Reppe, Vid Prijatelj, Kaare Morten Gautvik, Louise Falk, , Jonathan H. Tobias

This study uses GWAS and Mendelian randomization to show that lower sclerostin levels increase risk of hypertension, type 2 diabetes, myocardial infarction, and atherogenic lipid profiles.

Arthritis & Rheumatology · Apr 25, 2023Peer-reviewedGenetic & Genomic Medicine

The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip

Sarah Watkins, Karen M. Ho, Christian Testa, Louise Falk, Patrice Soule, Linda V. Nguyen, Sophie FitzGibbon, Catherine Slack, Jarvis T. Chen, George Davey Smith, Immaculata De Vivo, Andrew J. Simpkin, Kate M. Tilling, Pamela D. Waterman, Nancy Krieger, , Caroline Laura Relton

This study evaluates the reliability of DNA methylation measurements using the Illumina Infinium MethylationEPIC BeadChip at low DNA input levels, finding that 40ng DNA can be used with quality checks.

Epigenetics · Oct 14, 2022Peer-reviewedBioinformatics

Mendelian Randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures

Jie Zheng, Winfried Maerz, Ingrid Gergei, Marcus Edi Kleber, Christiane Drechsler, Christoph Wanner, Vincent Mathias Brandenburg, Sjur Reppe, Kaare Morten Gautvik, Carolina Medina‐Gómez, Enisa Shevroja, Arthur Gilly, Young‐Chan Park, George V. Dedoussis, Eleftheria Zeggini, , Jonathan H. Tobias

This paper uses Mendelian Randomization to show that higher circulating sclerostin levels causally reduce bone mineral density and increase fracture risk.

Journal of Bone and Mineral Research · Jun 6, 2019Peer-reviewedGenetics