Sarah Watkins

An epigenome-wide analysis of DNA methylation, racialized and economic inequities, and air pollution

This study investigates how DNA methylation (DNAm) links racial discrimination, economic adversity, and air pollution to health inequities using epigenome-wide association analyses.

Multi-omic triangulation identifies molecular candidates of atopic dermatitis severity

This study identifies 440 genes/proteins associated with atopic dermatitis severity through multi-omics analyses and highlights four with significant cross-evidence, including CEP85, which may contribute to severity via impaired phagocytosis.

Fathers' preconception smoking and offspring DNA methylation: A two generation study

This study identifies DNA methylation changes in offspring linked to fathers' preconception smoking, with specific CpG sites associated with asthma, wheezing, and BMI.

The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip

This study evaluates the reliability of DNA methylation measurements using the Illumina Infinium MethylationEPIC BeadChip at low DNA input levels, finding that 40ng DNA can be used with quality checks.

Grandmaternal smoking during pregnancy is associated with differential DNA methylation in their grandchildren

This study shows that grandmaternal smoking during pregnancy is linked to specific DNA methylation changes in grandchildren, with sex-specific effects on the X chromosome.

DNA co-methylation has a stable structure and is related to specific aspects of genome regulation

The paper investigates the stability and regulatory implications of DNA co-methylation across age and ancestry, finding stable patterns and links to transcription factor binding and chromatin interactions.