NeuroscienceMolecular TherapyPeer-reviewed
IL-1Ra and CCL5, but not IL-10, are promising targets for treating SMA astrocyte-driven pathology
Reilly L. Allison, Cecelia C Mangione, Mya Suneja…·Allison D. Ebert
This study identifies IL-1ra and CCL5 as potential therapeutic targets for SMA by showing they reduce astrocyte-driven inflammation and improve disease outcomes in vitro and in mice.
4 citations