Membrane-permeable 5-fluorodeoxyuridine triphosphate derivatives inhibit the proliferation of Plasmodium falciparum
Vella Nikolova, Karen Linnemannstöns, Marie-Elise Bendel, Marta Machado, Benedikt Ganter, Patricia Budimir, Michelle Vogts, Celine Fischer, Markus Ganter, Chris Meier, Matthias Dobbelstein
The paper tests cell-permeable 5-fluorodeoxyuridine triphosphate derivatives against Plasmodium falciparum and finds they inhibit parasite proliferation while being selectively rescued by thymidine in human cells.
ACS Infectious Diseases · Oct 3, 2025Peer-reviewedMicrobiology