Markus Ganter

This study identifies a mechanism of asynchronous nuclear division in Plasmodium falciparum that enhances proliferation by minimizing resource idling through sequential allocation of a limiting replication resource.

The paper introduces FLUMMI, a peptide marker for imaging internal membranes in Plasmodium without affecting viability, and shows its compatibility with live-cell and expansion microscopy.

The paper tests cell-permeable 5-fluorodeoxyuridine triphosphate derivatives against Plasmodium falciparum and finds they inhibit parasite proliferation while being selectively rescued by thymidine in human cells.

This study shows that RSL3 and Pyrimethamine synergistically inhibit Plasmodium falciparum growth, with a mechanism distinct from canonical ferroptosis.