LRRC57/RABIN is a presynaptic inhibitor of Rab GTPases in glutamatergic neurons
Dušan Garić, Jonathan G. Murphy, Brett J.W. Teubner, Christopher M. Davenport, Chablis D. Shreffler, Laura J. Janke, Woo Jung Cho, Zhiping Wu, Meghan G. McReynolds, Sarayut Phasuk, Jason Y. Fu, De'Keerah A. Lewis, Thomas Confer, Jonathon D. Klein, Melissa Johnson, , Stanislav S. Zakharenko
The paper identifies LRRC57/RABIN as a presynaptic inhibitor of Rab GTPases in glutamatergic neurons, showing it regulates neurotransmitter release and prevents epileptiform activity.
bioRxiv · Sep 28, 2026 · PreprintNeuroscience