In vivo epigenetic editing of sema6a promoter reverses impaired transcallosal connectivity caused by C11orf46/ARL14EP neurodevelopmental risk gene
Cyril Jayakumar Peter, Atsushi Saito, Yuto Hasegawa, Yuya Tanaka, Mohika Nagpal, Gabriel Perez, Emily Alway, Sergio Espeso‐Gil, Tariq Fayyad, Chana Ratner, Aslihan Dincer, Achla Gupta, Lakshmi A. Devi, John Pappas, François M. Lalonde, , Atsushi Kamiya
The paper shows that epigenetic editing of the Sema6a promoter can reverse impaired transcallosal connectivity caused by C11orf46 mutations.
Nature Communications · Sep 11, 2019Peer-reviewedDevelopmental Biology