Author

Yuto Hasegawa

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Atsushi KamiyaiD· 3 shared Akira SawaiD· 2 shared Achla GuptaiD· 1 shared Adrian G. PaeziD· 1 shared Amy K. SmithiD· 1 shared Andrew P. LaneiD· 1 shared Aslihan DinceriD· 1 shared Atsushi SaitoiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMolecular Biology

Atsushi KamiyaORCID

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3 papers

Recent·Most cited

Inflammation-related pathology in the olfactory epithelium: its impact on the olfactory system in psychotic disorders

Kun Yang, Yuto Hasegawa, Janardhan Prasad Bhattarai, Jun Hua, Milan Dower, Semra Etyemez, Neal Prasad, Lauren Duvall, Adrian G. Paez, Amy K. Smith, Yingqi Wang, Yun Feng Zhang, Andrew P. Lane, Koko Ishizuka, Vidyulata J. Kamath, , Akira Sawa

This study investigates how inflammation in the olfactory epithelium affects the olfactory bulb in schizophrenia and related disorders, finding correlations between immune-related gene expression and OB volume reduction.

Molecular Psychiatry · Feb 6, 2024Peer-reviewedMolecular Biology

Microglial cannabinoid receptor type1 mediates social memory deficits produced by adolescent THC exposure and 16p11.2 duplication

Yuto Hasegawa, Juhyun Kim, Gianluca Ursini, Yan Jouroukhin, Xiaolei Zhu, Yu Miyahara, Feiyi Xiong, Samskruthi Madireddy, Mizuho Obayashi, Beat Lutz, Akira Sawa, Solange Pezon Brown, Mikhail V. Pletnikov, Atsushi Kamiya

This study shows that adolescent THC exposure causes microglial apoptosis in the mPFC, which is worsened by 16p11.2 duplication, leading to social memory deficits via microglial Cnr1.

bioRxiv · Jul 24, 2023 · PreprintNeuroscience

In vivo epigenetic editing of sema6a promoter reverses impaired transcallosal connectivity caused by C11orf46/ARL14EP neurodevelopmental risk gene

Cyril Jayakumar Peter, Atsushi Saito, Yuto Hasegawa, Yuya Tanaka, Mohika Nagpal, Gabriel Perez, Emily Alway, Sergio Espeso‐Gil, Tariq Fayyad, Chana Ratner, Aslihan Dincer, Achla Gupta, Lakshmi A. Devi, John Pappas, François M. Lalonde, , Atsushi Kamiya

The paper shows that epigenetic editing of the Sema6a promoter can reverse impaired transcallosal connectivity caused by C11orf46 mutations.

Nature Communications · Sep 11, 2019Peer-reviewedDevelopmental Biology