Atsushi Kamiya

R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type specific transcription

The paper maps R-loop landscapes in the developing human brain and shows their role in neural differentiation and gene expression programs.

DISC1-PML protein interaction for congenital CMV infection-induced cortical neural progenitor deficit: perturbance of host signaling via viral IE1

This study identifies the role of CMV viral protein IE1 in disrupting host DISC1-PML interaction, leading to neural progenitor deficits in congenital CMV infection.

Inflammation-related pathology in the olfactory epithelium: its impact on the olfactory system in psychotic disorders

This study investigates how inflammation in the olfactory epithelium affects the olfactory bulb in schizophrenia and related disorders, finding correlations between immune-related gene expression and OB volume reduction.

Microglial cannabinoid receptor type1 mediates social memory deficits produced by adolescent THC exposure and 16p11.2 duplication

This study shows that adolescent THC exposure causes microglial apoptosis in the mPFC, which is worsened by 16p11.2 duplication, leading to social memory deficits via microglial Cnr1.

Human olfactory neuronal cells through nasal biopsy: molecular characterization and utility in brain science

This study characterizes olfactory neuronal cells from nasal biopsies using single-cell and bulk RNA sequencing, showing their neuronal similarity and utility in brain disorder research.

Brain-synthesized estrogens regulate cortical migration in a sexually divergent manner

This study shows that brain-synthesized estrogens affect cortical neuron migration differently in male and female mice through Cyp19a1 knockdown.

In vivo epigenetic editing of sema6a promoter reverses impaired transcallosal connectivity caused by C11orf46/ARL14EP neurodevelopmental risk gene

The paper shows that epigenetic editing of the Sema6a promoter can reverse impaired transcallosal connectivity caused by C11orf46 mutations.

The glutathione cycle shapes synaptic glutamate activity

The paper investigates the role of the glutathione cycle in regulating synaptic glutamate levels and excitatory neurotransmission, finding that glutathione acts as a reservoir for glutamate.