Knock-out of Tpm4.2/actin filaments alters neuronal signaling, neurite outgrowth and behavioral phenotypes in mice.
Sian Genoud, Chanchanok Chaichim, Rossana Rosa Porto, Tamara Tomanić, Holly Stefen, Esmeralda Parić, Soumalya Sarkar, Dasol Yoo, Wendi Gao, Edna C. Hardeman, Peter William Gunning, Tim Karl, John Power, Thomas Fath
This study investigates the role of Tpm4.2 in neuronal processes by analyzing knock-out mice, finding altered signaling, neurite outgrowth, and sex-dependent behavioral phenotypes.
Molecular Neurobiology · Aug 2, 2025Peer-reviewedNeuroscience