Author

Holly Stefen

Macquarie UniversityORCID 0000-0003-2027-2524Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Thomas FathiD· 3 shared Edna C. HardemaniD· 2 shared Esmeralda ParićiD· 2 shared Peter William GunningiD· 2 shared Tamara TomanićiD· 2 shared A. ChieniD· 1 shared Amr AbouelezziD· 1 shared Casper C. HoogenraadiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Thomas FathORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeuroscienceMolecular NeurobiologyPeer-reviewedAug 2, 2025

Knock-out of Tpm4.2/actin filaments alters neuronal signaling, neurite outgrowth and behavioral phenotypes in mice.

Sian Genoud, Chanchanok Chaichim, Rossana Rosa Porto…·Thomas Fath

This study investigates the role of Tpm4.2 in neuronal processes by analyzing knock-out mice, finding altered signaling, neurite outgrowth, and sex-dependent behavioral phenotypes.

3 citations

mouseelectronic health records

𝕏 PostBluesky

Cell BiologybioRxivPreprintJul 22, 2025

Fluorescence recovery after photobleaching reveals different 1 behaviour2 of tropomyosin isoforms Tpm3.1 and Tpm4.2 in dendritic spines

Tamara Tomanić, Holly Stefen, Esmeralda Parić…·Thomas Fath

This study uses FRAP to show Tpm3.1 and Tpm4.2 have distinct kinetic behaviors in dendritic spines and different effects on actin turnover.

DOI 10.1101/2025.07.22.666217

mousefluorescence / live-cell microscopy

𝕏 PostBluesky

NeuroscienceiSciencePeer-reviewedApr 12, 2020

Tropomyosin Tpm3.1 is required to maintain the structure and function of the axon initial segment

Amr Abouelezz, Holly Stefen, Mikael Segerstråle…·Pirta Hotulainen

This study identifies Tpm3.1 as essential for maintaining AIS structure and function by stabilizing actin filaments in the axon initial segment.

35 citations

mouseexperimental assay

𝕏 PostBluesky