John Power

This study investigates the role of Tpm4.2 in neuronal processes by analyzing knock-out mice, finding altered signaling, neurite outgrowth, and sex-dependent behavioral phenotypes.

This study shows that instrumental reward learning increases intrinsic excitability of BLA projection neurons, while punishment training maintains excitability and response-independent shocks reverse it.

This study investigates sex-dependent effects of chronic microdrive implantation on trace eyeblink conditioning in mice, finding that males learned faster than females with implants, but not with dummy implants.

The paper shows mice trade off decision speed for safety during approach-avoidance decisions under danger by adjusting activity in the paraventricular thalamus and prefrontal cortex.

This study shows that optogenetic inhibition of VTA dopamine neurons suppresses instrumental responding in a response-specific and contingency-sensitive manner, acting as an instrumental punisher.

This paper identifies the BLA[->]AcbSh pathway as critical for transitioning between appetitive seeking and consummatory behaviors in rats, showing it actively inhibits seeking during reward consumption.

The paper shows BLA PV interneurons report aversive prediction error and limit fear learning, while projection neurons form fear associations.

The paper identifies mesolimbic dopamine signatures associated with different forms of alcohol-seeking relapse using photometry and dissimilarity matrices.

The paper investigates how different ventral pallidum cell types and their projections contribute to relapse to alcohol-seeking in rats, identifying distinct roles for Gad1 and PV neurons.

This study shows that increasing KCC2 in mice reduces seizure-like activity and prevents status epilepticus, suggesting KCC2 targeting could help treat excitation-inhibition imbalances.

The paper shows that inhibiting BLA glutamatergic neurons during reinforcement or non-reinforcement reduces conditioned stimulus salience, affecting fear learning and behavior.