Simon Killcross

Representational geometry of punishment learning across basolateral amygdala neurons

This study examines how basolateral amygdala neuron activity changes during punishment learning in mice, showing that punishment learning alters action-related activity to align with punisher-specific responses.

Number, order and time influence how the brain integrates distinct experiences

The paper shows that the brain integrates distinct experiences based on the number, order, and timing of events across training stages in rats.

The brain architecture of punishment learning

This study maps how punishment learning reorganizes brain networks across scales using combined whole-brain analysis and spatial transcriptomics.

The basolateral amygdala complex and perirhinal cortex represent focal and peripheral states of information processing in rats

This study investigates how BLA and PRh contribute to learning about danger signals in rats, showing their distinct roles based on stimulus novelty and pairing with shock.

Integration of sensory and fear memories in the rat medial temporal lobe

The paper shows that the integration of sensory and fear memories in rats depends on the number of sensory pairings but not the brain circuitry involved.

The role of the rodent lateral orbitofrontal cortex in simple Pavlovian cue-outcome learning depends on training experience

This study investigates how rodent lateral OFC lesions affect Pavlovian cue-outcome learning, finding that pre-training lesions enhance acquisition while post-training lesions impair it.

The mesolimbic dopamine signatures of relapse to alcohol-seeking

The paper identifies mesolimbic dopamine signatures associated with different forms of alcohol-seeking relapse using photometry and dissimilarity matrices.

Medial Orbitofrontal Cortex Regulates Instrumental Conditioned Punishment, but not Pavlovian Conditioned Fear

This study shows that medial orbitofrontal cortex (mOFC) regulates instrumental conditioned punishment learning and retrieval, but not Pavlovian conditioned fear.

Complementary roles for ventral pallidum cell types and their projections in relapse

The paper investigates how different ventral pallidum cell types and their projections contribute to relapse to alcohol-seeking in rats, identifying distinct roles for Gad1 and PV neurons.

Punishment insensitivity emerges from impaired contingency detection, not aversion insensitivity or reward dominance

The paper shows punishment insensitivity in rats is due to impaired instrumental control, not aversion sensitivity or reward dominance.

The rodent lateral orbitofrontal cortex represents expected Pavlovian outcome value but not identity

This study investigates the role of the rodent lateral orbitofrontal cortex in outcome devaluation and reversal learning, finding dissociable effects between subregions and task types.