Chandra M. Panthi

Expanding the scope of Mycobacterium abscessus reference strains to improve pulmonary disease modeling

This study identifies Mab clinical isolates that better model human pulmonary disease compared to the commonly used ATCC 19977 strain in mouse models.

Efficacies of sequenced monotherapies of Mycobacterium avium lung infection in mouse

This study evaluates sequential monotherapy for M. avium lung infection in mice, finding it as effective as multidrug therapy without promoting resistance.

Combinations comprising dual β-lactams and a β-lactamase inhibitor achieve optimal synergistic inhibition of Mycobacterium abscessus growth

This study shows that combinations of dual β-lactams and β-lactamase inhibitors synergistically inhibit Mycobacterium abscessus growth, challenging the traditional view of their mechanisms.

Regimen comprising clarithromycin, clofazimine and bedaquiline is more efficacious than monotherapy in a mouse model of chronic Mycobacterium avium lung infection

The paper evaluates antibiotic regimens in a mouse model of M. avium infection, finding that a triple-drug regimen is more effective than monotherapy.