Spurious intragenic transcription is a hallmark of mammalian cellular senescence and tissue aging
Payel Sen, Greg Donahue, Changyin Li, Yemin Lan, Gabor Egervári, Neil Robertson, Parisha P. Shah, Erik Kerkhoven, D. Schultz, Peter D. Adams, Shelley L. Berger
This study identifies spurious intragenic transcription as a conserved hallmark of mammalian cellular senescence and tissue aging, impacting cellular health and transcriptional networks.
bioRxiv · May 20, 2022 · PreprintGenomics