Chunhui Hou

This paper introduces Dip3D, a method to reconstruct high-resolution diploid 3D human genomes from Pore-C data, achieving better performance than existing methods.

This study demonstrates that genomic rearrangements in yeast can be efficiently induced using SCRaMbLE, leading to diverse genetic changes and phenotypic effects.

Falign improves alignment of fragmented long noisy 3C data by addressing fragment boundary issues and increasing data utilization.

The paper introduces MOSAIC, a method to detect chromatin compartments, revealing micro-compartments that improve understanding of chromatin structure-function relationships.

This study analyzes chromatin architecture in Xenopus tropicalis, revealing TAD formation dynamics and conserved CTCF-Rad21 orientation patterns across vertebrates.

The paper identifies a systematic error in STARR-seq for enhancer activity measurement in Arabidopsis thaliana and proposes a solution using specialized primers to recover self-transcripts, revealing new insights into enhancer function.

The paper quantitatively identifies enhancers in the rice genome using STARR-seq and reports their genomic locations and epigenetic features.

This paper introduces an amplification-free Hi-C library preparation method that improves chromatin interaction quality and reduces sequencing depth requirements.